Introduction
Do you love isekai anime? Especially the best isekai anime with OP MCs!
Because I do! We love the Isekai concept for its extraordinary characters, storylines, and hidden messages they can teach us about our lives. If you believe even one of the things I mentioned, you will love today’s post. 😍
Well, because we’ve got the perfect list for you! We will discuss the top 21 best isekai anime with OP MCs!
Our isekai anime main characters tend to be overpowered! But the isekai anime I will give you will blow your mind with not just their unique skills and strength. But it shows different eccentricities of human characters.😋
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Don’t know what I am talking about? Let’s jump straight to our list, and I will explain the rest. Remember, I’m not listing them in any rank:
1. That Time I Got Reincarnated as a Slime – Season 3
That Time I Got Reincarnated as a Slime is one of those Isekai anime that has its cult fan-following 😎😎. And yup, this fantastic OP MC Isekai anime is back for the 3rd season finally! 😍😍😍 Yup, it’s the top isekai to watch in May 2025.
2. Solo Leveling
One of the best Korean manga written in my personal opinion 💥💥. And now, in the year 2025, after 1st season was completed, we can enjoy the Second Season of Solo Leveling.
Do not miss this anime if you are an isekai or fantasy anime genre lover overall.
Hope we get more seasons of Solo Leveling soon 🥳🥳🥳.
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3. Arifureta From Commonplace to World’s Strongest – Season 3
And finally, despite taking their sweet time, Season 3 of Arifureta is here! Currently running in November 2024 👏
As a top-tier Isekai anime 😎, we highly recommend you watch two seasons before you jump into the current season. Jam-packed with comedy, action, and romance — this anime is a must-watch for all isekai fans! 😝
Arifureta is one of my all-time favorites. And addictive to watch. This anime has everything a best isekai anime with OP MC 🤯 needs.
4. Seirei Gensouki: Spirit Chronicles
Yayyy! 😇😇 Finally new season of this OP MC here in 2024!
Must Watch 😱
This anime has a classic action-adventure vibe to the isekai anime plot, with our Haruto being super-OP. And like any amazing isekai anime, we have an array of characters you will love and hate. A must-watch for once at least!
5. Re Monster
A special new isekai anime for you is here! 😉👽👽
Re: Monster is an isekai anime 2024 that follows our hero/monster Tomokui Kanata, who, after an untimely death, is reincarnated as a lowly goblin. Fret not, though! 🤓🤓
He still retains his intelligence and memories from his past life. Along with the ability to absorb traits/skills from the creatures he consumes. As he feeds and grows stronger, he rises to become the goblin leader 📺👾
Yup! another isekai anime with OP MC for you all to watch! 😇😇
6. Headhunted to Another World: From Salaryman to Big Four
Another funny isekai🤩 with a twist since our hero is just a simple salaryman 😇.
Our isekai hero, Akira Oda, finds out it literally could be worse 🤣🤣 than being fired from a job.
Why do you ask?
Because Akira is headhunted by the Demon lord and hired to be the top brass of the demon army 😱. Goodbye spreadsheets, hello spellbooks!
Armed with intense meeting stamina, Akira climbs the ranks by managing monsters like they’re unruly coworkers. HR nightmares?😰 He’s got actual demons to handle. Office politics? Try actual politics—with assassins.
Top-notch comedy 😍😍. Part isekai, part chaos, as our protagonist redefines what it means to be “middle management in hell.”
7. A Journey Through Another World: Raising Kids While Adventuring
This is an isekai anime that is a slice-of-life & adventure genre 🤗, offering a heartwarming experience with OP MC and super cute kids 🥰.
Our protagonist Takumi Kayano is isekaid to the magical world of Etelldia 🤯. Equipped with magical powers, Takumi finds himself in the Forest of Gaia, where he encounters five-year-old twins, Allen and Elena, who possess extraordinary physical strength.
Our hero decides to take them under his wing and embarks on a grand adventure🤪 with them. Good isekai anime to watch if you are tired of serious anime. Have fun!🤘
8. Overlord Series
When I think about the best isekai anime with OP mc, Overlord is the first and one of the most popular anime that comes to my mind. Probably because the Fourth Season of Overlord is still going on as I am writing this!
This anime is unique.🌟
Why? Since our main character cannot fit into a bad guy or a good guy persona! His actions are mixed throughout the whole 4 seasons. With his immense powers, he saves people. But sometimes dooms them too.
All in all, the Overlord story goes beyond your typical Isekai adventure! Check it out! You won’t regret watching it.
9. I Was Reincarnated as the 7th Prince so I Can Take My Time Perfecting My Magical Ability
I Was Reincarnated as the 7th Prince is a captivating anime 🤩🤩 that follows the story of Lloyd. He is reincarnated as the seventh prince of Saloum.
With a perfect bloodline and extraordinary magical abilities, our OP MC Lloyd😱😱 embarks on a journey of self-discovery and magical mastery. Our hero navigates the challenges of his princely status while unraveling the complexities of power. This anime series promises us a blend of world-building, character intros, and intriguing conflicts that shape Lloyd’s path 🔥🔥.
So join Lloyd, our protagonist, on his quest to perfect his magical abilities and uncover the secrets of his new isekai life in a new world🎯🎯. Enjoy this new isekai anime in 2024.
10. The Wrong Way to Use Healing Magic
An incredible isekai anime of the year 2024 🥳🥳 and is currently ongoing as of the time of this article.
In this isekai journey, we follow Ken Usato–our main man of the hour– as he harnesses his rare healing magic abilities in a new world. As he and his friends face challenges and continue their self-discovery. A good balance of comedy, family, action, and adventure spices for all isekai fans 😇.
Watch and enjoy this tale of magic, friendship, and adventure. Highly recommended🤗🤗!
11. Parallel World Pharmacy
Falma, our hero of this anime, is OP but a very sweet kind of hero! This is probably one of the unique selling points from my perspective. 😁
With his limitless magic power and knowledge of medicine from his former life, our protagonist shines through this anime like nothing else. Quickly, this anime has made it into the hearts of people, and mine. 🤩 And despite being a new isekai anime, I believe it will grow more.
Hopefully, we will get a Parallel World Pharmacy 2 as well! 🎞️ No update on this series in 2024 yet.
12. Tsukimichi Moonlit Fantasy
Now, in the year 2024, this super fun isekai anime is officially the second season out for all isekai fans to watch.
I have seen a lot of isekai! Especially those isekai anime with OP MC. They are popular, but not all of them have as much to offer as this anime.
Moonlit Fantasy is one of those rare gems of isekai anime that is packed with all kinds of good stuff! Story characters, including our hero and his companions, are full of fun and adventure. Humor and action are well balanced with character arc, which is a rare joy! 🤭
Not to mention our hero Makoto is humble and funny despite being on par with the gods themselves! Which is fun in itself. So I recommend watching this anime at least once– you won’t regret it! I swear.
13. Saga of Tanya the Evil
By now, you must know I love comedy and action-rich Isekai anime over anything! Literally!🥰 But “Saga of Tanya the Evil” surprised me when I first watched this anime in my Isekai Anime 2021 binge.
This anime takes a whole different approach to the isekai anime reincarnation concept.
Our MC is cursed and given a girl-child body to be punished by “God X”. And despite that, Tanya Degurechaff fought to survive the war-torn isekai!
With her ruthlessness and OP magic skill, she fights not just for herself but for the nation. That kind of balances how her character behaves evilly sometimes!😈
I can drone on about how much this story and characters impressed, but no more spoilers! Go watch, guys! You will never regret it. God only knows when we will get its sequel. It’s already 2024 now 🥺.
14. She Professed Herself Pupil of the Wise Man
Usually, I’m not a big fan of gender-benders. But “She Professed Herself Pupil of the Wise Man” is a fantastic approach to what happens when our hero, Sakamori Kagami, also known as Danblf, is transported to the isekai world of Ark Earth Online.
But instead of his all-powerful avatar, he’s stuck in the body of a cute young girl! 😜
Yup! Fun starts early in this anime.
However, you never feel like our Hero/Heroine is still himself/herself. The character has some OP summoning skills to mow down her enemy! And with fun-filled comedy & great supporting characters, you never feel bored in this anime.
I wish all isekai anime fan who loves the whole Summoning hero/heroine genre must watch this anime! 😎
15. My Isekai Life: I Gained a Second Character Class and Became the Strongest Sage in the World
This anime is one of the new isekai anime of 2022! And boy, it’s an amazing adventure!
Our hero Yuuji is summoned into an isekai and is granted OP skills for taming monsters. With those skills, he goes on adventures and saves the world with his monster companions. A must-watch new isekai anime!
16. Skeleton Knight in Another World
This is again one of the new isekai anime of 2022 that has a great storyline and characters to boot. No new season in 2024 yet, though.
Our Hero Arc is OP, but at the same time uses his powers so innocently that it will make you laugh 🤣. Skeleton Knight in Another World is highly watch-worthy if you love comedy and action combo isekai anime. Like I do.🥰
17. Wise Man’s Grandchild
Wise Man’s Grandchild combines different key points of Isekai anime into one. With OP hero, comedy, action, and even a tidbit of romance. It offers a complete package to watch whenever you feel bored! 😁
18. How a Realist Hero Rebuilt the Kingdom
This anime is one of those unique isekai anime that gives a whole different experience to viewers. After watching two seasons of this series, I am still craving the next season of How a Realist Hero Rebuilt the Kingdom.
Sure, our Hero is a realist. But don’t let it fool you because I feel in the upcoming season we will see Souma’s OP skill at work. After all, we have already seen his strategies and intellect at work. 😎
Still awaiting another season of this fun and realistic Isekai anime in 2024!
19. In Another World With My Smartphone
What if you get light-struck by God? Accidentally, of course! 😄 and die!
That is what happens to our protagonist, Touy,a and he ends up with OP powers and his smartphone!
Why the smartphone? Well, to know you should watch the anime! Now in 2024, you can watch this series for two seasons together. Enjoy!
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20. How Not to Summon a Demon Lord
In How Not to Summon a Demon Lord, our hero is an otaku and shut-in who accidentally ended up in the world of Cross Reverie.
This anime is one of those isekai anime with OP MC, where the hero uses his OP powers but with a hilarious approach. Seriously! I still laugh so much whenever I rewatch this series. 😂
So why wait? Watch this anime for sure. You will have a blast! Still waiting for its next season in 2024.
21. Death March to the Parallel World Rhapsody
Ever wonder what happens when your hero is so OP that he seems invincible? Well, that’s pretty much true in Death March to the Parallel World Rhapsody 🤪.
Our hero, Satou, is transported to the isekai world where he is armed with an abundance of skills. But has no way to return to reality. So he sets out to explore this fantastical new world.
This story is filled with adventure and fun. I loved watching this one in my coding-break sessions.
Conclusion
Thanks for reading 🤗🤗!
We, at Be Problem Solver, hope you found this list of the Top 20 best Isekai anime with OP MCs! up to the task. If you enjoyed this list, we’d love for you to comment below and share this article on social media. 🙌
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Ta-da guys! Enjoy anime and keep coding! 👋
I loved this list! It’s great to see so many OP MCs spotlighted, especially with the updated picks for 2024. I can’t wait to start watching some of these new recommendations. Just finished “Re:Zero,” and I’m looking for something similar. Any thoughts on which ones blend humor and action well?
You can try the ever popular “One Punch Man series”. Even though it is not an isekai anime. It is full of humor and action.
I love this list! It’s always fun to see powerful MCs take charge in their new worlds. I’m especially excited to check out the newer titles you included—it’s nice to see how the genre continues to evolve. Great work!